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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: RADI_HUMAN




USC-OGP 2-DE database:  RADI_HUMAN


RADI_HUMAN


General information about the entry
View entry in simple text format
Entry nameRADI_HUMAN
Primary accession numberP35241
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Radixin;.
Gene nameName=RDX
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10}
Homo sapiens (Human)
UVEAL_MELANOMA_3-10
  map experimental info
 
UVEAL_MELANOMA_3-10

MAP LOCATIONS:
pI=6.09; Mw=84978

Cross-references
UniProtKB/Swiss-ProtP35241; RADI_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameRADI_HUMAN
Primary accession numberP35241
Secondary accession number(s) A7YIJ8 A7YIK0 A7YIK3 B7Z9U6 F5H1A7 Q86Y61
Sequence was last modified on February 1, 1994 (version 1)
Annotations were last modified on March 15, 2017 (version 163)
Name and origin of the protein
DescriptionRecName: Full=Radixin;
Gene nameName=RDX
Encoded onName=RDX
KeywordsActin capping; Actin-binding; Alternative splicing; Cell membrane; Complete proteome; Cytoplasm; Cytoskeleton; Deafness; Disease mutation; Membrane; Non-syndromic deafness; Phosphoprotein; Polymorphism; Reference proteome.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLL02320; AAA36541.1; -; mRNA
EMBLAK316061; BAH14432.1; -; mRNA
EMBLDQ916738; ABI34710.1; -; mRNA
EMBLDQ916739; ABI34711.1; -; mRNA
EMBLDQ916741; ABI34713.1; -; mRNA
EMBLDQ916742; ABI34714.1; -; mRNA
EMBLDQ916740; ABI34712.1; -; mRNA
EMBLAP000901; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLAP002788; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLCH471065; EAW67129.1; -; Genomic_DNA
EMBLBC047109; AAH47109.1; -; mRNA
CCDSCCDS58171.1; -. [P35241-2]; .
CCDSCCDS58172.1; -. [P35241-4]; .
CCDSCCDS58173.1; -. [P35241-3]; .
CCDSCCDS58174.1; -. [P35241-5]; .
CCDSCCDS8343.1; -. [P35241-1]; .
PIRA46127; A46127; .
RefSeqNP_001247421.1; NM_001260492.1. [P35241-5]; .
RefSeqNP_001247422.1; NM_001260493.1. [P35241-5]; .
RefSeqNP_001247423.1; NM_001260494.1. [P35241-4]; .
RefSeqNP_001247424.1; NM_001260495.1. [P35241-2]; .
RefSeqNP_001247425.1; NM_001260496.1. [P35241-3]; .
RefSeqNP_002897.1; NM_002906.3. [P35241-1]; .
UniGeneHs.263671; -; .
UniGeneHs.584560; -; .
UniGeneHs.741211; -; .
ProteinModelPortalP35241; -; .
SMRP35241; -; .
BioGrid111894; 71; .
IntActP35241; 11; .
MINTMINT-1536950; -; .
STRING9606.ENSP00000342830; -; .
iPTMnetP35241; -; .
PhosphoSitePlusP35241; -; .
SwissPalmP35241; -; .
BioMutaRDX; -; .
DMDM464541; -; .
EPDP35241; -; .
MaxQBP35241; -; .
PaxDbP35241; -; .
PeptideAtlasP35241; -; .
PRIDEP35241; -; .
EnsemblENST00000343115; ENSP00000342830; ENSG00000137710. [P35241-1]; .
EnsemblENST00000405097; ENSP00000384136; ENSG00000137710. [P35241-5]; .
EnsemblENST00000528498; ENSP00000432112; ENSG00000137710. [P35241-5]; .
EnsemblENST00000528900; ENSP00000433580; ENSG00000137710. [P35241-2]; .
EnsemblENST00000530301; ENSP00000436277; ENSG00000137710. [P35241-3]; .
EnsemblENST00000530749; ENSP00000437301; ENSG00000137710. [P35241-5]; .
EnsemblENST00000544551; ENSP00000445826; ENSG00000137710. [P35241-4]; .
GeneID5962; -; .
KEGGhsa:5962; -; .
UCSCuc001pku.4; human. [P35241-1]; .
CTD5962; -; .
DisGeNET5962; -; .
GeneCardsRDX; -; .
GeneReviewsRDX; -; .
HGNCHGNC:9944; RDX; .
HPACAB037312; -; .
HPAHPA000263; -; .
HPAHPA000763; -; .
MalaCardsRDX; -; .
MIM179410; gene; .
MIM611022; phenotype; .
neXtProtNX_P35241; -; .
OpenTargetsENSG00000137710; -; .
Orphanet90636; Autosomal recessive non-syndromic sensorineural deafness type DFNB; .
PharmGKBPA34311; -; .
eggNOGKOG3529; Eukaryota; .
eggNOGENOG410XQFP; LUCA; .
GeneTreeENSGT00860000133686; -; .
HOGENOMHOG000007113; -; .
HOVERGENHBG002185; -; .
InParanoidP35241; -; .
KOK05762; -; .
OMALSREDSM; -; .
OrthoDBEOG091G06UO; -; .
PhylomeDBP35241; -; .
TreeFamTF313935; -; .
ReactomeR-HSA-437239; Recycling pathway of L1; .
SIGNORP35241; -; .
ChiTaRSRDX; human; .
GeneWikiRadixin; -; .
GenomeRNAi5962; -; .
PROPR:P35241; -; .
ProteomesUP000005640; Chromosome 11; .
BgeeENSG00000137710; -; .
CleanExHS_RDX; -; .
ExpressionAtlasP35241; baseline and differential; .
GenevisibleP35241; HS; .
GOGO:0016324; C:apical plasma membrane; IDA:UniProtKB; .
GOGO:0071944; C:cell periphery; IDA:UniProtKB; .
GOGO:0051286; C:cell tip; IEA:Ensembl; .
GOGO:0005913; C:cell-cell adherens junction; IEA:Ensembl; .
GOGO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell; .
GOGO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB; .
GOGO:0070062; C:extracellular exosome; IDA:UniProtKB; .
GOGO:0005615; C:extracellular space; IDA:UniProtKB; .
GOGO:0019898; C:extrinsic component of membrane; IEA:InterPro; .
GOGO:0030175; C:filopodium; ISS:UniProtKB; .
GOGO:0005925; C:focal adhesion; IDA:UniProtKB; .
GOGO:0030027; C:lamellipodium; ISS:UniProtKB; .
GOGO:0005902; C:microvillus; ISS:UniProtKB; .
GOGO:0030496; C:midbody; IEA:Ensembl; .
GOGO:0043209; C:myelin sheath; IEA:Ensembl; .
GOGO:0005886; C:plasma membrane; IDA:HPA; .
GOGO:0001726; C:ruffle; IEA:Ensembl; .
GOGO:0032420; C:stereocilium; IEA:Ensembl; .
GOGO:0030315; C:T-tubule; IEA:Ensembl; .
GOGO:0003779; F:actin binding; IDA:UniProtKB; .
GOGO:0051117; F:ATPase binding; IPI:UniProtKB; .
GOGO:0045296; F:cadherin binding; IDA:BHF-UCL; .
GOGO:0042803; F:protein homodimerization activity; ISS:UniProtKB; .
GOGO:0051018; F:protein kinase A binding; ISS:UniProtKB; .
GOGO:0003723; F:RNA binding; IDA:UniProtKB; .
GOGO:0045176; P:apical protein localization; IEA:Ensembl; .
GOGO:0051016; P:barbed-end actin filament capping; IEA:Ensembl; .
GOGO:0036120; P:cellular response to platelet-derived growth factor stimulus; IEA:Ensembl; .
GOGO:0097067; P:cellular response to thyroid hormone stimulus; ISS:UniProtKB; .
GOGO:0061028; P:establishment of endothelial barrier; IGI:UniProtKB; .
GOGO:0045184; P:establishment of protein localization; ISS:UniProtKB; .
GOGO:0090002; P:establishment of protein localization to plasma membrane; IMP:UniProtKB; .
GOGO:0030033; P:microvillus assembly; IEA:Ensembl; .
GOGO:1903392; P:negative regulation of adherens junction organization; IMP:UniProtKB; .
GOGO:0045792; P:negative regulation of cell size; IMP:UniProtKB; .
GOGO:0034260; P:negative regulation of GTPase activity; IMP:UniProtKB; .
GOGO:0034111; P:negative regulation of homotypic cell-cell adhesion; IMP:UniProtKB; .
GOGO:0030335; P:positive regulation of cell migration; IMP:UniProtKB; .
GOGO:1903364; P:positive regulation of cellular protein catabolic process; IGI:UniProtKB; .
GOGO:2000643; P:positive regulation of early endosome to late endosome transport; IGI:UniProtKB; .
GOGO:1900087; P:positive regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB; .
GOGO:0010628; P:positive regulation of gene expression; IGI:UniProtKB; .
GOGO:1902966; P:positive regulation of protein localization to early endosome; IGI:UniProtKB; .
GOGO:0010737; P:protein kinase A signaling; ISS:UniProtKB; .
GOGO:0032231; P:regulation of actin filament bundle assembly; IMP:UniProtKB; .
GOGO:0008360; P:regulation of cell shape; IMP:UniProtKB; .
GOGO:0008361; P:regulation of cell size; IGI:UniProtKB; .
GOGO:0043087; P:regulation of GTPase activity; IGI:UniProtKB; .
GOGO:1902115; P:regulation of organelle assembly; IGI:UniProtKB; .
GOGO:0032487; P:regulation of Rap protein signal transduction; ISS:UniProtKB; .
GOGO:1900027; P:regulation of ruffle assembly; IMP:UniProtKB; .
Gene3D1.20.80.10; -; 1; .
Gene3D2.30.29.30; -; 1; .
InterProIPR019749; Band_41_domain; .
InterProIPR011174; ERM; .
InterProIPR011259; ERM_C_dom; .
InterProIPR000798; Ez/rad/moesin-like; .
InterProIPR014352; FERM/acyl-CoA-bd_prot_3-hlx; .
InterProIPR019748; FERM_central; .
InterProIPR019747; FERM_CS; .
InterProIPR000299; FERM_domain; .
InterProIPR018979; FERM_N; .
InterProIPR018980; FERM_PH-like_C; .
InterProIPR008954; Moesin_tail; .
InterProIPR011993; PH_dom-like; .
InterProIPR029071; Ubiquitin-rel_dom; .
PfamPF00769; ERM; 1; .
PfamPF09380; FERM_C; 1; .
PfamPF00373; FERM_M; 1; .
PfamPF09379; FERM_N; 1; .
PIRSFPIRSF002305; ERM; 1; .
PRINTSPR00935; BAND41; .
PRINTSPR00661; ERMFAMILY; .
SMARTSM00295; B41; 1; .
SMARTSM01196; FERM_C; 1; .
SUPFAMSSF47031; SSF47031; 1; .
SUPFAMSSF48678; SSF48678; 1; .
SUPFAMSSF50729; SSF50729; 1; .
SUPFAMSSF54236; SSF54236; 1; .
PROSITEPS00660; FERM_1; 1; .
PROSITEPS00661; FERM_2; 1; .
PROSITEPS50057; FERM_3; 1; .



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Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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